Abstract
Antiphospholipid syndrome (APS) involves multiple organ systems in the body with endocrine involvement being a rare manifestation. The first endocrine manifestation of APS is Adrenal insufficiency (AI) in the majority of the cases. AI being a fatal condition needs prompt diagnosis to avoid life threatening condition. Diagnosis of APS needs a combination of clinical features and laboratory investigations, whereas AI needs a low early morning serum cortisol level along with an elevated Adrenocorticotropic Hormone. Here we present a case of a 36-year-old female who had multiple vascular complications of APS in the form of fetal losses, Deep Vein Thrombosis, cerebrovascular accident, and AI due to adrenal infarct. Due to its rarity and nonspecific presentation, every case of adrenal hemorrhage (AH) and infarction with no known etiology should be evaluated for APS and screened with Lupus anticoagulant, anti-beta 2 microglobulin and anti-cardiolipin antibodies.
Published on: August 23, 2024
doi: 10.17756/micr.2024-106
Citation: Vignatha A, Viraajitha D, Shrilekha. 2024. Case Report of Antiphospholipid Syndrome Complicated with Adrenal Infraction. J Med Imaging Case Rep 8(1): 23-27.
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