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Clinical Evaluation of a Mitral Valve Simulation Application Used to Support Planning of Transcatheter Edge to Edge Repair Procedures

Klaus Fuglsang Kofoed, Michael Huy Cuong Pham, James Vincent Chapman, Jesper James Linde, Ole de Backer, Lars Valeur Køber, Fumimasa Shige, Gakuto Aoyama, and Takuya Sakaguchi
Background: Transcatheter mitral valve edge-to-edge repair (M-TEER) in the setting of severe mitral regurgitation (MR) has experienced increased usage in recent years. To select appropriate candidates and plan for these procedures, the cardiologist must predict likely procedural outcomes dependent on factors such as clip type, size, and position. We have proposed a method to utilize computed tomography (CT) images to generate a patient specific procedural simulation model that allows these variables to be tested to support clinical decision making in patients undergoing M-TEER procedures.

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A Comparison of Complication Rates between Transhepatic and Transperitoneal Percutaneous Cholecystostomy Routes in the Treatment of Acute Cholecystitis

Rebecca Hopkins, Alexandra Hodder and Andrew Dalton
Percutaneous cholecystostomy (PC) is an interventional radiology procedure used to treat gallbladder-related complications in patients who are poor surgical candidates for cholecystectomy. It can be performed via a transperitoneal (TP) or transhepatic (TH) approach, though the literature remains inconclusive on which route is superior.

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Comparing Efficacies of Drug-eluting versus Non-medicated Balloons in Arteriovenous Fistula Stenosis

Cassandra Collins, Alexandra Hodder and Andrew Dalton
Purpose: Arteriovenous fistulas (AVFs) are the preferred method for patients receiving hemodialysis treatment. However, AVFs are prone to developing stenosis, creating difficulties with proper functioning for hemodialysis. Percutaneous balloon angioplasty (PBA) is the mainstay of treatment for stenosis, yet there remains debate regarding the use of drug-eluting balloons (DEBs) containing paclitaxel compared to non-medicated balloons (NMBs).

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Slipped Proximal Humeral Epiphysis

Daniel Reyes, Jace Buxton and Scott Jorgensen

Background: Slipped proximal humeral epiphysis (SPHE) has rarely been described in the literature. In addition, to these authors’ knowledge, this condition has not previously been described in the literature as occurring following a fall such as occurred in this case. This contributes a potential mechanism of injury to this uncommon finding.

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Accurate Segmentation of Pigmented Skin Lesions Using Grounded-segment-anything

Takashi Nagaoka

Melanoma is a highly aggressive form of skin cancer, and accurately segmenting pigmented lesions is crucial for early diagnosis. However, manual annotation is time-consuming, subjective, and requires expertise from dermatologists. To address these challenges, we propose a fully unsupervised segmentation approach using grounded-segment-anything model (Grounded-SAM), which operates without the need for annotated training data.

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Preclinical Validation of Automatic Mitral Valve Segmentation and Measurement Technology for Planning Transcatheter Edge-to-edge Valve Repair Using Computed Tomography

Michael Huy Cuong Pham, Klaus Fuglsang Kofoed, James V. Chapman, Ole de Backer, Jesper J. Linde, Lars V. Køber, Gakuto Aoyama, Keitaro Kawashima and Takuya Sakaguchi

Mitral regurgitation (MR) is one of the most common valvular heart diseases, though many patients with severe MR are unsuitable for surgical interventions. Transcatheter edge-to-edge repair (TEER) is an established non-surgical procedure that allows safe and effective reduction of MR in highrisk patients. Appropriate patient selection is critical and achieved through clinical assessment and imaging derived measurement of the mitral valve (MV) apparatus to optimize procedural success.

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